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Gene PIK3CA
Variant N170S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PIK3CA N170S does not lie within any known functional domains of the Pik3ca protein (UniProt.org). N170S has not been characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA N170S

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Transcript NM_006218.4
gDNA chr3:g.179199846A>G
cDNA c.509A>G
Protein p.N170S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_006218.4 chr3:g.179199846A>G c.509A>G p.N170S RefSeq GRCh38/hg38
XM_011512894 chr3:g.179199846A>G c.509A>G p.N170S RefSeq GRCh38/hg38
XM_011512894.2 chr3:g.179199846A>G c.509A>G p.N170S RefSeq GRCh38/hg38
XM_006713658 chr3:g.179199846A>G c.509A>G p.N170S RefSeq GRCh38/hg38
XM_006713658.4 chr3:g.179199846A>G c.509A>G p.N170S RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179199846A>G c.509A>G p.N170S RefSeq GRCh38/hg38
NM_006218.3 chr3:g.179199846A>G c.509A>G p.N170S RefSeq GRCh38/hg38
NM_006218 chr3:g.179199846A>G c.509A>G p.N170S RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References