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Gene APC
Variant R1399F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC R1399F lies within the beta-catenin binding and downregulation region of the Apc protein (PMID: 14672538). R1399F has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC R1399F

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Transcript NM_000038.6
gDNA chr5:g.112839789_112839790delCGinsTT
cDNA c.4195_4196delCGinsTT
Protein p.R1399F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001127510.2 chr5:g.112839789_112839790delCGinsTT c.4195_4196delCGinsTT p.R1399F RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112839789_112839790delCGinsTT c.4195_4196delCGinsTT p.R1399F RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112839789_112839790delCGinsTT c.4195_4196delCGinsTT p.R1399F RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112839789_112839790delCGinsTT c.4195_4196delCGinsTT p.R1399F RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112839789_112839790delCGinsTT c.4195_4196delCGinsTT p.R1399F RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112839789_112839790delCGinsTT c.4195_4196delCGinsTT p.R1399F RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112839789_112839790delCGinsTT c.4195_4196delCGinsTT p.R1399F RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
APC R1399F unknown