FGFR2 K41E
Gene Variant Detail

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Gene FGFR2
Variant K41E
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions FGFR2 K41E lies within Ig-like C2-type domain 1 of the Fgfr2 protein (UniProt.org). K41E results in decreased Fgfr2 expression, but demonstrates subcellular localization, basal and ligand-dependent Erk phosphorylation levels similar to wild-type Fgfr2 in culture (PMID: 30761385), and therefore, is predicted to have no effect on Fgfr2 protein function.
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 K41E

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Transcript NM_000141.5
gDNA chr10:g.121565693T>C
cDNA c.121A>G
Protein p.K41E
Source Database RefSeq
Genome Build GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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