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Gene ATR
Variant S1142G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATR S1142G does not lie within any known functional domains of the Atr protein (UniProt.org). S1142G has not been characterized in the scientific literature and therefore, its effect on Atr protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR S1142G

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Transcript NM_001184.4
gDNA chr3:g.142542691T>C
cDNA c.3424A>G
Protein p.S1142G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047448364.1 chr3:g.142542691T>C c.3424A>G p.S1142G RefSeq GRCh38/hg38
XM_047448360.1 chr3:g.142542691T>C c.3424A>G p.S1142G RefSeq GRCh38/hg38
XM_011512924.1 chr3:g.142542691T>C c.3424A>G p.S1142G RefSeq GRCh38/hg38
NM_001184.3 chr3:g.142542691T>C c.3424A>G p.S1142G RefSeq GRCh38/hg38
NM_001184.4 chr3:g.142542691T>C c.3424A>G p.S1142G RefSeq GRCh38/hg38
XM_047448362.1 chr3:g.142542691T>C c.3424A>G p.S1142G RefSeq GRCh38/hg38
XM_047448361.1 chr3:g.142542691T>C c.3424A>G p.S1142G RefSeq GRCh38/hg38
XM_047448363.1 chr3:g.142542691T>C c.3424A>G p.S1142G RefSeq GRCh38/hg38
XM_011512924.2 chr3:g.142542691T>C c.3424A>G p.S1142G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References