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| Gene | ATR |
| Variant | S1142G |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | ATR S1142G does not lie within any known functional domains of the Atr protein (UniProt.org). S1142G has been identified in the scientific literature (PMID: 15987455, PMID: 33257393), but has not been biochemically characterized and therefore, its effect on Atr protein function is unknown (PubMed, Sep 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
ATR mutant ATR S1142G |
| Transcript | NM_001184.4 |
| gDNA | chr3:g.142542691T>C |
| cDNA | c.3424A>G |
| Protein | p.S1142G |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_001184.4 | chr3:g.142542691T>C | c.3424A>G | p.S1142G | RefSeq | GRCh38/hg38 |
| XM_047448361.1 | chr3:g.142542691T>C | c.3424A>G | p.S1142G | RefSeq | GRCh38/hg38 |
| XM_047448360.1 | chr3:g.142542691T>C | c.3424A>G | p.S1142G | RefSeq | GRCh38/hg38 |
| XM_047448363.1 | chr3:g.142542691T>C | c.3424A>G | p.S1142G | RefSeq | GRCh38/hg38 |
| XM_047448362.1 | chr3:g.142542691T>C | c.3424A>G | p.S1142G | RefSeq | GRCh38/hg38 |
| NM_001184.3 | chr3:g.142542691T>C | c.3424A>G | p.S1142G | RefSeq | GRCh38/hg38 |
| XM_011512924.2 | chr3:g.142542691T>C | c.3424A>G | p.S1142G | RefSeq | GRCh38/hg38 |
| XM_047448364.1 | chr3:g.142542691T>C | c.3424A>G | p.S1142G | RefSeq | GRCh38/hg38 |
| XM_011512924.1 | chr3:g.142542691T>C | c.3424A>G | p.S1142G | RefSeq | GRCh38/hg38 |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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