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Gene MSH6
Variant E946D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MSH6 E946D lies within the clamp domain of the Msh6 protein (PMID: 17531815). E946D has not been characterized in the scientific literature and therefore, its effect on Msh6 protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

MSH6 mutant MSH6 E946D

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Transcript NM_000179.3
gDNA chr2:g.47800821A>C
cDNA c.2838A>C
Protein p.E946D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406800.1 chr2:g.47800821A>C c.2838A>C p.E946D RefSeq GRCh38/hg38
NM_000179.2 chr2:g.47800821A>C c.2838A>C p.E946D RefSeq GRCh38/hg38
XM_024452819.1 chr2:g.47800821A>C c.2838A>C p.E946D RefSeq GRCh38/hg38
NM_001406796.1 chr2:g.47800821A>C c.2838A>C p.E946D RefSeq GRCh38/hg38
NM_001406799.1 chr2:g.47803610G>C c.2838G>C p.E946D RefSeq GRCh38/hg38
NM_001406806.1 chr2:g.47803610G>C c.2838G>C p.E946D RefSeq GRCh38/hg38
NM_001406803.1 chr2:g.47806259A>C c.2838A>C p.E946D RefSeq GRCh38/hg38
NM_001406809.1 chr2:g.47800821A>C c.2838A>C p.E946D RefSeq GRCh38/hg38
NM_001406808.1 chr2:g.47800821A>C c.2838A>C p.E946D RefSeq GRCh38/hg38
NM_001406798.1 chr2:g.47800821A>C c.2838A>C p.E946D RefSeq GRCh38/hg38
NM_001406807.1 chr2:g.47803610G>C c.2838G>C p.E946D RefSeq GRCh38/hg38
NM_000179.3 chr2:g.47800821A>C c.2838A>C p.E946D RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries