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Gene TP53
Variant S362C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions TP53 S362C lies within the CARM1, HIPK1, and USP7-interacting regions of the Tp53 protein (UniProt.org). S362C has not been characterized in the scientific literature and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon10 TP53 S362C

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Transcript NM_000546.6
gDNA chr17:g.7670625T>A
cDNA c.1084A>T
Protein p.S362C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000546.5 chr17:g.7670625T>A c.1084A>T p.S362C RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7670625T>A c.1084A>T p.S362C RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7670625T>A c.1084A>T p.S362C RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7670625T>A c.1084A>T p.S362C RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7670625T>A c.1084A>T p.S362C RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7670625T>A c.1084A>T p.S362C RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7670625T>A c.1084A>T p.S362C RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References