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Gene | ROS1 |
Variant | P671Q |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 P671Q lies within fibronectin type-III domain 3 of the Ros1 protein (UniProt.org). P671Q has not been characterized in the scientific literature and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 P671Q |
Transcript | NM_002944.3 |
gDNA | chr6:g.117387782G>T |
cDNA | c.2012C>A |
Protein | p.P671Q |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_011536052.2 | chr6:g.117386987G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
NM_001378891.1 | chr6:g.117386987G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
XM_006715548.5 | chr6:g.117386987G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
XM_047419232.1 | chr6:g.117386987G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
XM_011536051.2 | chr6:g.117387782G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
NM_002944.2 | chr6:g.117387782G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
NM_002944.3 | chr6:g.117387782G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
XM_011536051.3 | chr6:g.117387782G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
NM_001378902.1 | chr6:g.117386987G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
XM_006715548.4 | chr6:g.117386987G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
XM_047419231.1 | chr6:g.117386987G>T | c.2012C>A | p.P671Q | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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