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Gene | TP53 |
Variant | V173dup |
Impact List | duplication |
Protein Effect | unknown |
Gene Variant Descriptions | TP53 V173dup indicates the insertion of the duplicate amino acid, valine (V)-173, in the DNA-binding domain of the Tp53 protein (PMID: 22713868). V173dup has not been characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2025). |
Associated Drug Resistance | |
Category Variants Paths |
TP53 mutant TP53 exon5 TP53 V173dup |
Transcript | NM_000546.6 |
gDNA | chr17:g.7675093_7675095 |
cDNA | c.517_519 |
Protein | p.V173 |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |