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Gene ATR
Variant L1397M
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATR L1397M does not lie within any known functional domains of the Atr protein (UniProt.org). L1397M has not been characterized in the scientific literature and therefore, its effect on Atr protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR L1397M

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Transcript NM_001184.4
gDNA chr3:g.142522805A>T
cDNA c.4189T>A
Protein p.L1397M
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001184.4 chr3:g.142522805A>T c.4189T>A p.L1397M RefSeq GRCh38/hg38
XM_047448363.1 chr3:g.142522805A>T c.4189T>A p.L1397M RefSeq GRCh38/hg38
NM_001184.3 chr3:g.142522805A>T c.4189T>A p.L1397M RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References