FGFR1 M563I
Gene Variant Detail

Request Content

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene FGFR1
Variant M563I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 M563I (corresponds to M532I in the canonical isoform) lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). M563I has been identified in the scientific literature (PMID: 32622884), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, May 2025).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 M563I

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_001174067.2
gDNA chr8:g.38417373C>G
cDNA c.1689G>C
Protein p.M563I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011544445.2 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
NM_001174067.2 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_017013219.2 chr8:g.38417367C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_017013220.1 chr8:g.38417367C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544445.3 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_017013219.1 chr8:g.38417367C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544447.2 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544444.2 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544444.1 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_017013220.2 chr8:g.38417367C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544447.3 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
NM_001174067.1 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References