FGFR1 M563I - Gene Variant Detail

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Gene FGFR1
Variant M563I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 M563I (corresponds to M532I in the canonical isoform) lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). M563I has been identified in the scientific literature (PMID: 32622884), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 M563I

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Transcript NM_001174067.2
gDNA chr8:g.38417373C>G
cDNA c.1689G>C
Protein p.M563I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017013219.2 chr8:g.38417367C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
NM_001174067.1 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544445.3 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_017013220.1 chr8:g.38417367C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
NM_001174067.2 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544444.2 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544444.1 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544447.2 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_017013220.2 chr8:g.38417367C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_017013219.1 chr8:g.38417367C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544447.3 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38
XM_011544445.2 chr8:g.38417373C>G c.1689G>C p.M563I RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References