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Gene FGFR1
Variant K687E
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 K687E (corresponds to K656E in the canonical isoform) lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). K687E has been identified in the scientific literature (PMID: 32622884, PMID: 34250399, PMID: 35952322), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 K687E

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Transcript NM_001174067.2
gDNA chr8:g.38414790T>C
cDNA c.2059A>G
Protein p.K687E
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011544445.2 chr8:g.38414790T>C c.2059A>G p.K687E RefSeq GRCh38/hg38
XM_011544447.2 chr8:g.38414790T>C c.2059A>G p.K687E RefSeq GRCh38/hg38
XM_011544447.3 chr8:g.38414790T>C c.2059A>G p.K687E RefSeq GRCh38/hg38
NM_001174067.2 chr8:g.38414790T>C c.2059A>G p.K687E RefSeq GRCh38/hg38
XM_011544444.2 chr8:g.38414790T>C c.2059A>G p.K687E RefSeq GRCh38/hg38
NM_001174067.1 chr8:g.38414790T>C c.2059A>G p.K687E RefSeq GRCh38/hg38
XM_011544445.3 chr8:g.38414790T>C c.2059A>G p.K687E RefSeq GRCh38/hg38
XM_011544444.1 chr8:g.38414790T>C c.2059A>G p.K687E RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries