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| Gene | MLH1 |
| Variant | hypermethylation |
| Impact List | unknown |
| Protein Effect | unknown |
| Gene Variant Descriptions | MLH1 hypermethylation indicates an increased methylation of the MLH1 gene. However, the mechanism causing the hypermethylation is unspecified. |
| Associated Drug Resistance | |
| Category Variants Paths |
MLH1 hypermethylation |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT04774419 | Phase II | Dostarlimab-gxly | Radiation and TSR-042 (Dostarlimab) in People With Endometrial Cancer After They Receive Surgery | Recruiting | USA | 0 |