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Gene CTNNB1
Variant V22_G38del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions CTNNB1 V22_G38del results in the deletion of 17 amino acids in the ubiquitination recognition motif of the Ctnnb1 protein from amino acids 22 to 38 (PMID: 15064718). V22_G38del has been identified in sequencing studies (PMID: 11282485, PMID: 25157968), but has not been biochemically characterized and therefore, its effect on Ctnnb1 protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

CTNNB1 mutant CTNNB1 V22_G38del

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Transcript NM_001098210.2
gDNA chr3:g.41224577_41224627del51
cDNA c.65_115del51
Protein p.V22_G38del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017005738.2 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_006712985 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_017005738.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_024453357.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
NM_001098209.2 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
NM_001904.4 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_024453356.2 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
NM_001904.3 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
NM_001098210 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_047447480.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
NM_001098210.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_047447479.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_006712985.2 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_047447483.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_047447477.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_024453358.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
NM_001098209.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
NM_001098210.2 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_005264886 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_047447481.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_047447478.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
NM_001904 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_006712985.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
NM_001098209 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_024453356.1 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38
XM_017005738 chr3:g.41224577_41224627del51 c.65_115del51 p.V22_G38del RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References