Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | ROS1 |
Variant | A1964T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 A1964T lies within the protein kinase domain of the Ros1 protein (UniProt.org). A1964T has been identified in sequencing studies (PMID: 22810696), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 A1964T |
Transcript | NM_002944.3 |
gDNA | chr6:g.117319918C>T |
cDNA | c.5890G>A |
Protein | p.A1964T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_017011173 | chr6:g.117319876C>T | c.5890G>A | p.A1964T | RefSeq | GRCh38/hg38 |
NM_002944.2 | chr6:g.117319918C>T | c.5890G>A | p.A1964T | RefSeq | GRCh38/hg38 |
XM_017011173.1 | chr6:g.117319876C>T | c.5890G>A | p.A1964T | RefSeq | GRCh38/hg38 |
NM_002944.3 | chr6:g.117319918C>T | c.5890G>A | p.A1964T | RefSeq | GRCh38/hg38 |
XM_011536050 | chr6:g.117319945C>T | c.5890G>A | p.A1964T | RefSeq | GRCh38/hg38 |
NM_002944 | chr6:g.117319918C>T | c.5890G>A | p.A1964T | RefSeq | GRCh38/hg38 |
XM_017011173.2 | chr6:g.117319876C>T | c.5890G>A | p.A1964T | RefSeq | GRCh38/hg38 |
XM_011536050.3 | chr6:g.117319945C>T | c.5890G>A | p.A1964T | RefSeq | GRCh38/hg38 |
XM_011536050.2 | chr6:g.117319945C>T | c.5890G>A | p.A1964T | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
---|