Gene Variant Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene CTNNB1
Variant R18_R151delinsS
Impact List indel
Protein Effect unknown
Gene Variant Descriptions CTNNB1 R18_R151delinsS results in a deletion of 134 amino acids of the Ctnnb1 protein from aa 18 to aa 151, combined with the insertion of serine (S) at the same site (UniProt.org). R18_R151delinsS has not been characterized in the scientific literature and therefore, its effect on Ctnnb1 protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

CTNNB1 mutant CTNNB1 R18_R151delinsS

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_001098210.2
gDNA chr3:g.41224566_41225164del599
cDNA c.54_452del599
Protein .
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001098210.1 chr3:g.41224566_41225164del599 c.54_452del599 p.R18_R151delinsS RefSeq GRCh38/hg38
NM_001904.4 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
NM_001098210.2 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
XM_006712985.2 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
XM_017005738.2 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
NM_001098209.2 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
XM_047447479.1 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
XM_047447480.1 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
XM_047447483.1 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
XM_024453356.2 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
XM_047447477.1 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
XM_047447478.1 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38
XM_047447481.1 chr3:g.41224566_41225164del599 c.54_452del599 . RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References