Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | ROS1 |
Variant | V1729L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 V1729L lies within fibronectin type-III domain 8 of the Ros1 protein (UniProt.org). V1729L has not been characterized in the scientific literature and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 V1729L |
Transcript | NM_002944.3 |
gDNA | chr6:g.117337235C>G |
cDNA | c.5185G>C |
Protein | p.V1729L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002944.3 | chr6:g.117337235C>G | c.5185G>C | p.V1729L | RefSeq | GRCh38/hg38 |
NM_002944 | chr6:g.117337235C>G | c.5185G>C | p.V1729L | RefSeq | GRCh38/hg38 |
NM_002944.2 | chr6:g.117337235C>G | c.5185G>C | p.V1729L | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|