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Gene | ROS1 |
Variant | R2096W |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 R2096W lies within the protein kinase domain of the Ros1 protein (UniProt.org). R2096W has been identified in sequencing studies (PMID: 24413735), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 R2096W |
Transcript | NM_002944.3 |
gDNA | chr6:g.117310229G>A |
cDNA | c.6286C>T |
Protein | p.R2096W |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002944 | chr6:g.117310229G>A | c.6286C>T | p.R2096W | RefSeq | GRCh38/hg38 |
NM_002944.3 | chr6:g.117310229G>A | c.6286C>T | p.R2096W | RefSeq | GRCh38/hg38 |
NM_002944.2 | chr6:g.117310229G>A | c.6286C>T | p.R2096W | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
ROS1 R2096W | unknown |