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Gene ROS1
Variant R2078W
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ROS1 R2078W lies within the protein kinase domain of the Ros1 protein (UniProt.org). R2078W has not been characterized in the scientific literature and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

ROS1 mutant ROS1 R2078W

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Transcript NM_002944.3
gDNA chr6:g.117311021T>A
cDNA c.6232A>T
Protein p.R2078W
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006715548 chr6:g.117310266_117310268delTCTinsCCA c.6232_6234delAGAinsTGG p.R2078W RefSeq GRCh38/hg38
NM_002944.2 chr6:g.117311021T>A c.6232A>T p.R2078W RefSeq GRCh38/hg38
XM_011536053.3 chr6:g.117310139G>A c.6232C>T p.R2078W RefSeq GRCh38/hg38
XM_006715548.5 chr6:g.117310266_117310268delAGAinsTGG c.6232_6234delAGAinsTGG p.R2078W RefSeq GRCh38/hg38
NM_002944 chr6:g.117311021T>A c.6232A>T p.R2078W RefSeq GRCh38/hg38
NM_002944.3 chr6:g.117311021T>A c.6232A>T p.R2078W RefSeq GRCh38/hg38
XM_006715548.4 chr6:g.117310266_117310268delAGAinsTGG c.6232_6234delAGAinsTGG p.R2078W RefSeq GRCh38/hg38
XM_011536053 chr6:g.117310139G>A c.6232C>T p.R2078W RefSeq GRCh38/hg38
XM_011536053.2 chr6:g.117310139G>A c.6232C>T p.R2078W RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
ROS1 R2078W unknown