KDR S338Y
Gene Variant Detail

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Gene KDR
Variant S338Y
Impact List missense
Protein Effect unknown
Gene Variant Descriptions KDR (VEGFR2) S338Y lies within Ig-like C2-type domain 4 of the Kdr (Vegfr2) protein (UniProt.org). S338Y has been identified in sequencing studies (PMID: 22810696), but has not been biochemically characterized and therefore, its effect on Kdr (Vegfr2) protein function is unknown (PubMed, Jun 2026).
Associated Drug Resistance
Category Variants Paths

KDR mutant KDR S338Y

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Transcript NM_002253.4
gDNA chr4:g.55110732G>T
cDNA c.1013C>A
Protein p.S338Y
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002253.3 chr4:g.55110732G>T c.1013C>A p.S338Y RefSeq GRCh38/hg38
NM_002253.4 chr4:g.55110732G>T c.1013C>A p.S338Y RefSeq GRCh38/hg38
NM_002253 chr4:g.55110732G>T c.1013C>A p.S338Y RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References