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Gene | ROS1 |
Variant | P2130T |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 P2130T lies within the protein kinase domain of the Ros1 protein (UniProt.org). P2130T has not been characterized in the scientific literature and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 P2130T |
Transcript | NM_002944.3 |
gDNA | chr6:g.117310127G>T |
cDNA | c.6388C>A |
Protein | p.P2130T |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002944.2 | chr6:g.117310127G>T | c.6388C>A | p.P2130T | RefSeq | GRCh38/hg38 |
NM_002944 | chr6:g.117310127G>T | c.6388C>A | p.P2130T | RefSeq | GRCh38/hg38 |
NM_002944.3 | chr6:g.117310127G>T | c.6388C>A | p.P2130T | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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