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Gene | ROS1 |
Variant | P1440L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 P1440L lies within the extracellular domain of the Ros1 protein (UniProt.org). P1440L has been identified in sequencing studies (PMID: 22842228), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 P1440L |
Transcript | NM_002944.3 |
gDNA | chr6:g.117352992G>A |
cDNA | c.4319C>T |
Protein | p.P1440L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002944.2 | chr6:g.117352992G>A | c.4319C>T | p.P1440L | RefSeq | GRCh38/hg38 |
XM_017011173.1 | chr6:g.117344223G>A | c.4319C>T | p.P1440L | RefSeq | GRCh38/hg38 |
NM_002944 | chr6:g.117352992G>A | c.4319C>T | p.P1440L | RefSeq | GRCh38/hg38 |
XM_017011173.2 | chr6:g.117344223G>A | c.4319C>T | p.P1440L | RefSeq | GRCh38/hg38 |
NM_002944.3 | chr6:g.117352992G>A | c.4319C>T | p.P1440L | RefSeq | GRCh38/hg38 |
XM_017011173 | chr6:g.117344223G>A | c.4319C>T | p.P1440L | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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