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Gene ROS1
Variant P1440S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ROS1 P1440S lies within the extracellular domain of the Ros1 protein (UniProt.org). P1440S has not been characterized in the scientific literature and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

ROS1 mutant ROS1 P1440S

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Transcript NM_002944.3
gDNA chr6:g.117352993G>A
cDNA c.4318C>T
Protein p.P1440S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017011173.1 chr6:g.117344224G>A c.4318C>T p.P1440S RefSeq GRCh38/hg38
XM_017011173.2 chr6:g.117344224G>A c.4318C>T p.P1440S RefSeq GRCh38/hg38
NM_002944.3 chr6:g.117352993G>A c.4318C>T p.P1440S RefSeq GRCh38/hg38
NM_002944.2 chr6:g.117352993G>A c.4318C>T p.P1440S RefSeq GRCh38/hg38
XM_017011173 chr6:g.117344224G>A c.4318C>T p.P1440S RefSeq GRCh38/hg38
NM_002944 chr6:g.117352993G>A c.4318C>T p.P1440S RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References