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Gene PTEN
Variant T167A
Impact List missense
Protein Effect loss of function
Gene Variant Descriptions PTEN T167A lies within the phosphatase tensin-type domain of the Pten protein (UniProt.org). T176A results in decreased phosphatase activity and partial inhibition of Pi3k activity in an yeast assay (PMID: 21828076).
Associated Drug Resistance
Category Variants Paths

PTEN mutant PTEN inact mut PTEN T167A

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Transcript NM_000314.8
gDNA chr10:g.87952124A>G
cDNA c.499A>G
Protein p.T167A
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000314 chr10:g.87952124A>G c.499A>G p.T167A RefSeq GRCh38/hg38
NM_000314.6 chr10:g.87952124A>G c.499A>G p.T167A RefSeq GRCh38/hg38
NM_000314.8 chr10:g.87952124A>G c.499A>G p.T167A RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries