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Gene HRAS
Variant Y157F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS Y157F does not lie within any known functional domains of the Hras protein (UniProt.org). Y157F has not been characterized in the scientific literature and therefore, its effect on Hras protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS Y157F

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Transcript NM_005343.4
gDNA chr11:g.532736T>A
cDNA c.470A>T
Protein p.Y157F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005343.4 chr11:g.532736T>A c.470A>T p.Y157F RefSeq GRCh38/hg38
NM_001130442.3 chr11:g.532736T>A c.470A>T p.Y157F RefSeq GRCh38/hg38
NM_001130442.2 chr11:g.532736T>A c.470A>T p.Y157F RefSeq GRCh38/hg38
NM_005343.3 chr11:g.532736T>A c.470A>T p.Y157F RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References