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Gene PTEN
Variant Q214_F215del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions PTEN Q214_F215del results in the deletion of two amino acids in the C2 tensin-type domain of the Pten protein from amino acids 214 to 215 (UniProt.org). Q214_F215del has not been characterized in the scientific literature and therefore, its effect on Pten protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

PTEN mutant PTEN Q214_F215del

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Transcript NM_000314.8
gDNA chr10:g.87957858_87957863delCAGTTT
cDNA c.640_645delCAGTTT
Protein p.Q214_F215del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000314.6 chr10:g.87957858_87957863delCAGTTT c.640_645delCAGTTT p.Q214_F215del RefSeq GRCh38/hg38
NM_000314.8 chr10:g.87957858_87957863delCAGTTT c.640_645delCAGTTT p.Q214_F215del RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References