ROS1 V1979A
Gene Variant Detail

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Gene ROS1
Variant V1979A
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ROS1 V1979A lies within the protein kinase domain of the Ros1 protein (UniProt.org). V1979A has been identified in the scientific literature (PMID: 34907086), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Aug 2025).
Associated Drug Resistance
Category Variants Paths

ROS1 mutant ROS1 V1979A

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Transcript NM_002944.3
gDNA chr6:g.117319872A>G
cDNA c.5936T>C
Protein p.V1979A
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002944.2 chr6:g.117319872A>G c.5936T>C p.V1979A RefSeq GRCh38/hg38
NM_002944.3 chr6:g.117319872A>G c.5936T>C p.V1979A RefSeq GRCh38/hg38
XM_011536050.3 chr6:g.117319899A>G c.5936T>C p.V1979A RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References