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Gene MSH6
Variant Q776H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions MSH6 Q776H lies within the lever domain of the Msh6 protein (PMID: 17531815). Q776H has not been characterized in the scientific literature and therefore, its effect on Msh6 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

MSH6 mutant MSH6 Q776H

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Transcript NM_000179.3
gDNA chr2:g.47800311A>T
cDNA c.2328A>T
Protein p.Q776H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001406808.1 chr2:g.47800311A>T c.2328A>T p.Q776H RefSeq GRCh38/hg38
NM_001406798.1 chr2:g.47800311A>T c.2328A>T p.Q776H RefSeq GRCh38/hg38
NM_001406800.1 chr2:g.47800311A>T c.2328A>T p.Q776H RefSeq GRCh38/hg38
XM_024452819.1 chr2:g.47800311A>T c.2328A>T p.Q776H RefSeq GRCh38/hg38
NM_000179.2 chr2:g.47800311A>T c.2328A>T p.Q776H RefSeq GRCh38/hg38
NM_001406809.1 chr2:g.47800311A>T c.2328A>T p.Q776H RefSeq GRCh38/hg38
NM_001406796.1 chr2:g.47800311A>T c.2328A>T p.Q776H RefSeq GRCh38/hg38
NM_000179.3 chr2:g.47800311A>T c.2328A>T p.Q776H RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References