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Gene ATR
Variant E2626*
Impact List nonsense
Protein Effect unknown
Gene Variant Descriptions ATR E2626* results in a premature truncation of the Atr protein at amino acid 2626 of 2644 (UniProt.org). E2626* has been identified in sequencing studies (PMID: 34568053), but has not been biochemically characterized and therefore, its effect on Atr protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR E2626*

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Transcript NM_001184.4
gDNA chr3:g.142449488C>A
cDNA c.7876G>T
Protein p.E2626*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001184.4 chr3:g.142449488C>A c.7876G>T p.E2626* RefSeq GRCh38/hg38
NM_001184.3 chr3:g.142449488C>A c.7876G>T p.E2626* RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References