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Gene APC
Variant H2116R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC H2116R does not lie within any known functional domains of the Apc protein (UniProt.org). H2116R has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC H2116R

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Transcript NM_000038.6
gDNA chr5:g.112841941A>G
cDNA c.6347A>G
Protein p.H2116R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354895.1 chr5:g.112841941A>G c.6347A>G p.H2116R RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112841941A>G c.6347A>G p.H2116R RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112841941A>G c.6347A>G p.H2116R RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112841941A>G c.6347A>G p.H2116R RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112841941A>G c.6347A>G p.H2116R RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112841941A>G c.6347A>G p.H2116R RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112841941A>G c.6347A>G p.H2116R RefSeq GRCh38/hg38

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References