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Gene APC
Variant A1225G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC A1225G lies within a region of the Apc protein responsible for downregulation mediated by ubiquitination (UniProt.org). A1225G has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC A1225G

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Transcript NM_000038.6
gDNA chr5:g.112839268C>G
cDNA c.3674C>G
Protein p.A1225G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354895.1 chr5:g.112839268C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_001354902.2 chr5:g.112839541C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_001407470.1 chr5:g.112840117C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112839268C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_001354906.2 chr5:g.112840117C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112839268C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112839268C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112839268C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112839268C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_001354904.2 chr5:g.112839646C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112839268C>G c.3674C>G p.A1225G RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References