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Gene CDKN2A
Variant A109P
Impact List missense
Protein Effect loss of function
Gene Variant Descriptions CDKN2A A109P does not lie within any known functional domains of the Cdkn2a protein (UniProt.org). A109P confers a loss of function to Cdkn2a as demonstrated by failure to inhibit proliferation and cell cycle progression in culture (PMID: 35001868).
Associated Drug Resistance
Category Variants Paths

CDKN2A mutant CDKN2A inact mut CDKN2A A109P

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Transcript NM_000077.5
gDNA chr9:g.21971034C>G
cDNA c.325G>C
Protein p.A109P
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011517676.3 chr9:g.21971034C>G c.325G>C p.A109P RefSeq GRCh38/hg38
XM_011517676.2 chr9:g.21971034C>G c.325G>C p.A109P RefSeq GRCh38/hg38
NM_000077.5 chr9:g.21971034C>G c.325G>C p.A109P RefSeq GRCh38/hg38
XM_011517675.2 chr9:g.21971034C>G c.325G>C p.A109P RefSeq GRCh38/hg38
XM_011517675.3 chr9:g.21971034C>G c.325G>C p.A109P RefSeq GRCh38/hg38
NM_001195132.1 chr9:g.21971034C>G c.325G>C p.A109P RefSeq GRCh38/hg38
NM_058197.5 chr9:g.21974503C>G c.325G>C p.A109P RefSeq GRCh38/hg38
NM_000077.4 chr9:g.21971034C>G c.325G>C p.A109P RefSeq GRCh38/hg38
NM_001195132.2 chr9:g.21971034C>G c.325G>C p.A109P RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries