ERBB3 G325R
Gene Variant Detail

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Gene ERBB3
Variant G325R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ERBB3 (HER3) G325R lies within the extracellular domain of the Erbb3 (Her3) protein (UniProt.org). G325R has been identified in the scientific literature (PMID: 35503762), but has not been biochemically characterized and therefore, its effect on Erbb3 (Her3) protein function is unknown (PubMed, Jan 2026).
Associated Drug Resistance
Category Variants Paths

ERBB3 mutant ERBB3 G325R

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Transcript NM_001982.4
gDNA chr12:g.56088641G>A
cDNA c.973G>A
Protein p.G325R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001982.4 chr12:g.56088641G>A c.973G>A p.G325R RefSeq GRCh38/hg38
NM_001982.3 chr12:g.56088641G>A c.973G>A p.G325R RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References