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Gene FGFR2
Variant M121V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 M121V lies within Ig-like C2-type domain 1 of the Fgfr2 protein (UniProt.org). M121V has not been characterized in the scientific literature and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 M121V

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Transcript NM_000141.5
gDNA chr10:g.121565453T>C
cDNA c.361A>G
Protein p.M121V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001320658.2 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_022970.4 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_001144917.1 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_001144914.1 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_001144914.1 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_022970.3 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38
NM_001144917.2 chr10:g.121565453T>C c.361A>G p.M121V RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References