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Gene APC
Variant Q2372*
Impact List nonsense
Protein Effect unknown
Gene Variant Descriptions APC Q2372* results in a premature truncation of the Apc protein at amino acid 2372 of 2843 (UniProt.org). Q2372* has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC Q2372*

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Transcript NM_000038.6
gDNA chr5:g.112842708C>T
cDNA c.7114C>T
Protein p.Q2372*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001407446.1 chr5:g.112842624C>T c.7114C>T p.Q2372* RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112842708C>T c.7114C>T p.Q2372* RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112842708C>T c.7114C>T p.Q2372* RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112842708C>T c.7114C>T p.Q2372* RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112842708C>T c.7114C>T p.Q2372* RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112842708C>T c.7114C>T p.Q2372* RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112842708C>T c.7114C>T p.Q2372* RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112842708C>T c.7114C>T p.Q2372* RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References