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Gene APC
Variant L508F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC L508F lies within ARM repeat 2 of the Apc protein (UniProt.org). L508F has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC L508F

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Transcript NM_000038.6
gDNA chr5:g.112827223G>T
cDNA c.1524G>T
Protein p.L508F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001127510.3 chr5:g.112827223G>T c.1524G>T p.L508F RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112827223G>T c.1524G>T p.L508F RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112827223G>T c.1524G>T p.L508F RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112827223G>T c.1524G>T p.L508F RefSeq GRCh38/hg38
NM_001354898.1 chr5:g.112827977_112827979delCTAinsTTT c.1522_1524delCTAinsTTT p.L508F RefSeq GRCh38/hg38
NM_000038 chr5:g.112827223G>T c.1524G>T p.L508F RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112827223G>T c.1524G>T p.L508F RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112827223G>T c.1524G>T p.L508F RefSeq GRCh38/hg38
NM_001127510 chr5:g.112827223G>T c.1524G>T p.L508F RefSeq GRCh38/hg38
NM_001354898.2 chr5:g.112827977_112827979delCTAinsTTT c.1522_1524delCTAinsTTT p.L508F RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112827223G>T c.1524G>T p.L508F RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries