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Gene APC
Variant P1432H
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC P1432H lies within the beta-catenin binding and downregulation region of the Apc protein (PMID: 14672538). P1432H has been identified in sequencing studies (PMID: 17558858), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC P1432H

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Transcript NM_000038.6
gDNA chr5:g.112839889_112839890delCAinsAT
cDNA c.4295_4296delCAinsAT
Protein p.P1432H
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001127510.3 chr5:g.112839889_112839890delCAinsAT c.4295_4296delCAinsAT p.P1432H RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112839889_112839890delCAinsAT c.4295_4296delCAinsAT p.P1432H RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112839889_112839890delCAinsAT c.4295_4296delCAinsAT p.P1432H RefSeq GRCh38/hg38
NM_000038 chr5:g.112839889_112839890delCAinsAT c.4295_4296delCAinsAT p.P1432H RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112839889_112839890delCAinsAT c.4295_4296delCAinsAT p.P1432H RefSeq GRCh38/hg38
NM_001407451.1 chr5:g.112839910C>A c.4295C>A p.P1432H RefSeq GRCh38/hg38
NM_001127510 chr5:g.112839889_112839890delCAinsAT c.4295_4296delCAinsAT p.P1432H RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112839889_112839890delCAinsAT c.4295_4296delCAinsAT p.P1432H RefSeq GRCh38/hg38
NM_001407452.1 chr5:g.112839919C>A c.4295C>A p.P1432H RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112839889_112839890delCAinsAT c.4295_4296delCAinsAT p.P1432H RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112839889_112839890delCAinsAT c.4295_4296delCAinsAT p.P1432H RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
APC P1432H unknown