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Gene | PTEN |
Variant | F241L |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | PTEN F241L lies within the C2 tensin-type domain of the Pten protein (UniProt.org). F241L has not been characterized in the scientific literature and therefore, its effect on Pten protein function is unknown (PubMed, Jan 2024). |
Associated Drug Resistance | |
Category Variants Paths |
PTEN mutant PTEN F241L |
Transcript | NM_000314.8 |
gDNA | chr10:g.87957939T>C |
cDNA | c.721T>C |
Protein | p.F241L |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_000314.8 | chr10:g.87957939T>C | c.721T>C | p.F241L | RefSeq | GRCh38/hg38 |
NM_000314.6 | chr10:g.87957939T>C | c.721T>C | p.F241L | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
PTEN F241L | unknown |