TP53 N239_C242del
Gene Variant Detail

Request Content

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene TP53
Variant N239_C242del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions TP53 N239_C242del results in the deletion of four amino acids in the DNA-binding domain of the Tp53 protein from amino acids 239 to 242 (PMID: 22713868). N239_C242del has been identified in the scientific literature (PMID: 38140788 ), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Sep 2025).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon7 TP53 N239_C242del

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_000546.6
gDNA chr17:g.7674237_7674248del12
cDNA c.716_727del12
Protein p.N239_C242del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001126113.3 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_000546.6 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7674237_7674248del12 c.716_727del12 p.N239_C242del RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries