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Gene | FLT3 |
Variant | H721Y |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FLT3 H721Y lies within the protein kinase domain of the Flt3 protein (UniProt.org). H721Y has been identified in the scientific literature (PMID: 32040554), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, Sep 2024). |
Associated Drug Resistance | |
Category Variants Paths |
FLT3 mutant FLT3 exon17 FLT3 H721Y |
Transcript | NM_004119.3 |
gDNA | chr13:g.28027134G>A |
cDNA | c.2161C>T |
Protein | p.H721Y |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004119.3 | chr13:g.28027134G>A | c.2161C>T | p.H721Y | RefSeq | GRCh38/hg38 |
NM_004119.2 | chr13:g.28027134G>A | c.2161C>T | p.H721Y | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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