FLT3 M837I
Gene Variant Detail

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Gene FLT3
Variant M837I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FLT3 M837I lies within the protein kinase domain of the Flt3 protein (UniProt.org). M837I has been identified in the scientific literature (PMID: 32040554), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, Jun 2025).
Associated Drug Resistance
Category Variants Paths

FLT3 mutant FLT3 exon20 FLT3 M837I

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Transcript NM_004119.3
gDNA chr13:g.28018497C>G
cDNA c.2511G>C
Protein p.M837I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004119.2 chr13:g.28018497C>G c.2511G>C p.M837I RefSeq GRCh38/hg38
NM_004119.3 chr13:g.28018497C>G c.2511G>C p.M837I RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References