FLT3 M837K
Gene Variant Detail

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Gene FLT3
Variant M837K
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FLT3 M837K lies within the protein kinase domain of the Flt3 protein (UniProt.org). M837K has been identified in the scientific literature (PMID: 32040554, PMID: 31088841), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, Jul 2025).
Associated Drug Resistance
Category Variants Paths

FLT3 mutant FLT3 exon20 FLT3 M837K

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Transcript NM_004119.3
gDNA chr13:g.28018498A>T
cDNA c.2510T>A
Protein p.M837K
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004119.3 chr13:g.28018498A>T c.2510T>A p.M837K RefSeq GRCh38/hg38
NM_004119.2 chr13:g.28018498A>T c.2510T>A p.M837K RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References