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Gene | PIK3CA |
Variant | W11_P18del |
Impact List | deletion |
Protein Effect | unknown |
Gene Variant Descriptions | PIK3CA W11_P18del results in the deletion of eight amino acids of the Pik3ca protein from amino acids 11 to 18 (UniProt.org). W11_P18del has not been characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, May 2024). |
Associated Drug Resistance | |
Category Variants Paths |
PIK3CA mutant PIK3CA W11_P18del |
Transcript | NM_006218.4 |
gDNA | chr3:g.179198856_179198879del24 |
cDNA | c.31_54del24 |
Protein | p.W11_P18del |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_006218.3 | chr3:g.179198856_179198879del24 | c.31_54del24 | p.W11_P18del | RefSeq | GRCh38/hg38 |
XM_006713658.5 | chr3:g.179198856_179198879del24 | c.31_54del24 | p.W11_P18del | RefSeq | GRCh38/hg38 |
NM_006218.4 | chr3:g.179198856_179198879del24 | c.31_54del24 | p.W11_P18del | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
PIK3CA W11_P18del | unknown |