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Gene | PTEN |
Variant | H61Y |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | PTEN H61Y lies within the phosphatase tensin-type domain of the Pten protein (UniProt.org). H61Y has been identified in the scientific literature (PMID: 21470976, PMID: 18215105), but has not been biochemically characterized and therefore, its effect on Pten protein function is unknown (PubMed, Dec 2023). |
Associated Drug Resistance | |
Category Variants Paths |
PTEN mutant PTEN H61Y |
Transcript | NM_000314.8 |
gDNA | chr10:g.87925529C>T |
cDNA | c.181C>T |
Protein | p.H61Y |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_000314.8 | chr10:g.87925529C>T | c.181C>T | p.H61Y | RefSeq | GRCh38/hg38 |
NM_000314.6 | chr10:g.87925529C>T | c.181C>T | p.H61Y | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
PTEN H61Y | unknown |