PTEN S170G
Gene Variant Detail

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Gene PTEN
Variant S170G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PTEN S170G lies within the phosphatase tensin-type domain of the Pten protein (UniProt.org). S170G has not been characterized and therefore, its effect on Pten protein function is unknown (PubMed, Jul 2025).
Associated Drug Resistance
Category Variants Paths

PTEN mutant PTEN S170G

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Transcript NM_000314.8
gDNA chr10:g.87952133A>G
cDNA c.508A>G
Protein p.S170G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000314.8 chr10:g.87952133A>G c.508A>G p.S170G RefSeq GRCh38/hg38
NM_000314.6 chr10:g.87952133A>G c.508A>G p.S170G RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References