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Gene PTEN
Variant Y346D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PTEN Y346D lies within the C2 tensin-type domain of the Pten protein (UniProt.org). Y346D has not been characterized and therefore, its effect on Pten protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

PTEN mutant PTEN Y346D

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Transcript NM_000314.8
gDNA chr10:g.87965296T>G
cDNA c.1036T>G
Protein p.Y346D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000314.8 chr10:g.87965296T>G c.1036T>G p.Y346D RefSeq GRCh38/hg38
NM_000314.6 chr10:g.87965296T>G c.1036T>G p.Y346D RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References