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Gene CDKN2A
Variant L32_L37del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions CDKN2A L32_L37del results in the deletion of six amino acids in ANK repeat 1 of the Cdkn2a protein from amino acids 32 to 37 (UniProt.org). L32_L37del has been identified in the scientific literature (PMID: 33050356), but has not been biochemically characterized and therefore, its effect on Cdkn2a protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

CDKN2A mutant CDKN2A L32_L37del

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Transcript NM_000077.5
gDNA chr9:g.21974725_21974742del18
cDNA c.95_112del18
Protein p.L32_L37delLEAGAL
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001195132.2 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37delLEAGAL RefSeq GRCh38/hg38
NM_001195132.1 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37del RefSeq GRCh38/hg38
NM_001363763.2 chr9:g.21971096_21971113del18 c.94_111del18 p.H32_E37delHDAARE RefSeq GRCh38/hg38
XM_047422597.1 chr9:g.21971096_21971113del18 c.94_111del18 p.H32_E37delHDAARE RefSeq GRCh38/hg38
XM_011517675.3 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37delLEAGAL RefSeq GRCh38/hg38
XM_011517676.2 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37del RefSeq GRCh38/hg38
XM_047422598.1 chr9:g.21971096_21971113del18 c.94_111del18 p.H32_E37delHDAARE RefSeq GRCh38/hg38
NM_000077.5 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37delLEAGAL RefSeq GRCh38/hg38
NM_058195.4 chr9:g.21994221_21994238del18 c.98_115del18 p.E33_G38delEWAAPG RefSeq GRCh38/hg38
NM_000077.4 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37del RefSeq GRCh38/hg38
NM_058197.5 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37delLEAGAL RefSeq GRCh38/hg38
NM_058197.4 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37del RefSeq GRCh38/hg38
XM_011517675.2 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37del RefSeq GRCh38/hg38
XM_011517676.3 chr9:g.21974725_21974742del18 c.95_112del18 p.L32_L37delLEAGAL RefSeq GRCh38/hg38
XM_047422596.1 chr9:g.21971096_21971113del18 c.94_111del18 p.H32_E37delHDAARE RefSeq GRCh38/hg38

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References