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Gene CDKN2A
Variant N42K
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CDKN2A N42K does not lie within any known functional domains of the Cdkn2a protein (UniProt.org). N42K has been identified in the scientific literature (PMID: 31741767), but has not been biochemically characterized and therefore, its effect on Cdkn2a protein function is unknown (PubMed, Jun 2024).
Associated Drug Resistance
Category Variants Paths

CDKN2A mutant CDKN2A N42K

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Transcript NM_000077.5
gDNA chr9:g.21974702A>C
cDNA c.126T>G
Protein p.N42K
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011517676.2 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38
NM_000077.4 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38
NM_058197.4 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38
NM_058197.5 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38
NM_001195132.1 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38
NM_000077.5 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38
XM_011517676.3 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38
XM_011517675.3 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38
XM_011517675.2 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38
NM_001195132.2 chr9:g.21974702A>C c.126T>G p.N42K RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References