Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Gene | CDKN2A |
Variant | P114F |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | CDKN2A P114F lies within ANK repeat 4 of the Cdkn2a protein (UniProt.org). P114F has not been characterized in the scientific literature and therefore, its effect on Cdkn2a protein function is unknown (PubMed, Jun 2024). |
Associated Drug Resistance | |
Category Variants Paths |
CDKN2A mutant CDKN2A P114F |
Transcript | NM_000077.5 |
gDNA | chr9:g.21971018_21971019delCCinsTT |
cDNA | c.340_341delCCinsTT |
Protein | p.P114F |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
XM_011517676.2 | chr9:g.21971018_21971019delCCinsTT | c.340_341delCCinsTT | p.P114F | RefSeq | GRCh38/hg38 |
NM_001195132.1 | chr9:g.21971018_21971019delCCinsTT | c.340_341delCCinsTT | p.P114F | RefSeq | GRCh38/hg38 |
NM_001195132.2 | chr9:g.21971018_21971019delCCinsTT | c.340_341delCCinsTT | p.P114F | RefSeq | GRCh38/hg38 |
XM_011517675.2 | chr9:g.21971018_21971019delCCinsTT | c.340_341delCCinsTT | p.P114F | RefSeq | GRCh38/hg38 |
NM_000077.5 | chr9:g.21971018_21971019delCCinsTT | c.340_341delCCinsTT | p.P114F | RefSeq | GRCh38/hg38 |
XM_011517675.3 | chr9:g.21971018_21971019delCCinsTT | c.340_341delCCinsTT | p.P114F | RefSeq | GRCh38/hg38 |
NM_000077.4 | chr9:g.21971018_21971019delCCinsTT | c.340_341delCCinsTT | p.P114F | RefSeq | GRCh38/hg38 |
XM_011517676.3 | chr9:g.21971018_21971019delCCinsTT | c.340_341delCCinsTT | p.P114F | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|