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Gene PIK3CA
Variant E39G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PIK3CA E39G lies within the PI3K-ABD domain of the Pik3ca protein (UniProt.org). E39G has been identified in sequencing studies (PMID: 28528867), but has not been biochemically characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, Dec 2023).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA E39G

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Transcript NM_006218.4
gDNA chr3:g.179198941A>G
cDNA c.116A>G
Protein p.E39G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006713658.5 chr3:g.179198941A>G c.116A>G p.E39G RefSeq GRCh38/hg38
XM_006713658.4 chr3:g.179198941A>G c.116A>G p.E39G RefSeq GRCh38/hg38
NM_006218.4 chr3:g.179198941A>G c.116A>G p.E39G RefSeq GRCh38/hg38
XM_011512894.2 chr3:g.179198941A>G c.116A>G p.E39G RefSeq GRCh38/hg38
NM_006218.3 chr3:g.179198941A>G c.116A>G p.E39G RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References